A large increase in monocytes, called monocytosis, in an old dog often means the body is fighting a long-term infection, chronic inflammation, tissue damage, or certain types of cancer like leukemia or immune-mediated diseases. It is a sign that the immune system is working hard.
Causes of Monocytosis
- Chronic infections: Fungal or bacterial issues that last a long time.
- Immune-mediated disease: The body attacks its own cells.
- Tissue necrosis: Dead or dying tissue from injury or tumors.
- Neoplasia: Cancers like lymphoma or monocytic leukemia.
- Stress or steroids: High stress levels or certain drugs.
Next Steps for Care
- See a vet: Get a full physical exam.
- Run more tests: Do blood panels, X-rays, or an ultrasound.
- Find the root cause: Treat the specific disease or infection found.
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