Friday, August 14, 2026

6788. Monocytosis in an old dog with hair loss

 

A large increase in monocytes, called monocytosis, in an old dog often means the body is fighting a long-term infection, chronic inflammation, tissue damage, or certain types of cancer like leukemia or immune-mediated diseases. It is a sign that the immune system is working hard.
Causes of Monocytosis
  • Chronic infections: Fungal or bacterial issues that last a long time.
  • Immune-mediated disease: The body attacks its own cells.
  • Tissue necrosis: Dead or dying tissue from injury or tumors.
  • Neoplasia: Cancers like lymphoma or monocytic leukemia.
  • Stress or steroids: High stress levels or certain drugs.
Next Steps for Care
  • See a vet: Get a full physical exam.
  • Run more tests: Do blood panels, X-rays, or an ultrasound.
  • Find the root cause: Treat the specific disease or infection found.

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