4480. Myanmar. Immune disease Alsatian

 Immune mediated haemolytic anemia suspect in over 2 years old male GSD.

 

 I will send blood tests and detail history and clinical signs next day.

 

 Over 2 years old intact male GSD presented with lethergy, reduced appetite and weight loss, jaundice.
Dog had tick infestation last 5months and owner gave Simparica tablet that's for external parasites.
Then, gradually reduced appetite and weight.

At the time I do physical examination, the dog is too weak, jaundice and also mild dehydration.
I assumed that jaundice might be due to hemolysis rather than liver issue. So, I check CBC, PCV and liver panel.
And Anemia+ as the result of CBC.
Reticulocyte+ in CBC, so, regeneration is noted.

Jaundice+ Anemia
So, the underlying cause of anemia in this case might be RBC breakdown rather than reduced production and ongoing blood loss.
So, as differential diagnosis, the underlying problem might be..

- Sepsis
- Blood parasites
- neoplasia
- Autoimmune


The dog hasn't any sign of sepsis.
Negative for Snap4Dx test
Didn't see any tumor mass in X-ray.

So, that over 2years old GSD might have immune mediated haemolytic anemia in my opinion.

 

 PCV 16% today.
Still searching for donor. Haven't got  yet.
The dog is on saline drip, vitamin and iron supplement, and prednisolone 1mg/kg S/C BD.